Zantac is one of many medications used to decrease the symptoms of heartburn. In exchange, however, some patients might develop cancer or experience Zantac cancer symptoms. If you or loved one has already taken Zantac learn what your legal options are with an experienced product liability lawyer today.
The risk of cancer from Zantac use is simply too great to ignore. We are a law firm focused on holding manufacturers of dangerous drugs responsible for their corporate negligence. It is our earnest belief that Sanofi failed to warn consumers of the unacceptable levels of a potential human carcinogen (substance that promotes formation of cancer).
The American College of Gastroenterology reports that as many as 60 million Americans suffer from heartburn each month. Considering this fact, it is no wonder that drug manufacturers are cashing in on their discomfort. While people who suffer from heartburn can reduce or eliminate their symptoms through dietary changes and stress management, these methods tend only to work over time.
Is Zantac Still On The Market?
Valisure, an independent pharmacy conducted an extensive study of ranitidine (generic form of Zantac) in 2019. Their findings illustrated that a single ranitidine tablet contains in excess of 300,000 nanograms of N-Nitrosodimethylamine (NDMA). To put that in proper context, the acceptable level of NDMA is 96 nanograms per single tablet. Thus, a single dosage of Zantac contained 3000 times the acceptable level of NDMA. Hence, why the the Food and Drug Administration (FDA) pulled all versions of this popular heartburn drugs from shelves on April 1, 2020. The FDA determined the risk of allowing Zantac to remain on the shelves is simply too great to the safety of consumers.
NDMA Linked to Certain Cancers
The concern with NDMA is that it can potentially cause cancer, even in small amounts. The longer the exposure to this carcinogen, the higher the chances are for developing cancer and other health problems such as liver disease. Rodent studies revealed a consistent carcinogenic effect of NDMA. The rate of hepatic, pulmonary, and renal tumors has been shown to increase in rodents with inhalation of NDMA and consumption in drinking water containing NDMA.
NDMA is one of the most potent animal carcinogens known to date. It has proven to be a potent carcinogen for all species that were studied, both as single doses and with long-term exposure to smaller quantities. Of note, NDMA seems to be metabolized in the same way in human tissue and rodent tissue. Because of this, the International Agency for Research on Cancer (IARC) classifies NDMA as probably carcinogenic to humans (Group 2A), highlighting that, for practical purposes, NDMA should be viewed as if it were carcinogenic to humans.
NDMA exposure from ranitidine is also linked to several other cancers such as:
- Stomach cancer
- Cancer in the small and large intestines
- Colorectal cancer
- Esophageal cancer
- Kidney cancer
- Bladder cancer
- Liver cancer
- Prostate cancer
- Pancreatic cancer
- Non-Hodgkin’s lymphoma
- Multiple myeloma
- Islet cell tumors
- Breast cancer
- Intestinal cancer
- Throat/nasal cancer
- Brain cancer
Ranitidine and Cancer
The main ingredient in Zantac is ranitidine hydrochloride. Ranitidine is classified as part of a group of antacid drugs known as H2 blockers. In 2004, the National Cancer Institute published a study linking bladder cancer with ranitidine use. A 2016 study, illustrates the use of ranitidine significantly increases the presence of NDMA in urinary excretion. This was a groundbreaking study published in the medical journal Carcinogenesis. We are already representing numerous Zantac bladder cancer victims. Sibley Dolman is investigating numerous links between women presently undergoing breast cancer treatment whom used Zantac for an extended period of time.
In October of 2019, two major drug companies Apotex and Navartis stated they were pulling all versions of generic ranitidine sold over the counter and via prescription throughout the U.S. Ranitidine is better known by the brand name Zantac was created by Sanofi and is sold both over the counter at drug stores and pharmacies throughout the U.S. and can be prescribed at a much stronger level.
The FDA found via testing, the levels of NDMA in ranitidine increase over time even when stored under normal conditions at room temperature. It was the mere fact that a known carcinogen could increase within ranitidine over a finite period of time that prompted the FDA to order Zantac to be taken off the shelves.
There is increasing date suggesting a correlation between ranitidine and cancer. Researchers at Memorial Sloan Kettering Cancer Center are presently studying the link between ranitidine and various types of cancer.
Zantac Liver Cancer
There is also anecdotal evidence that Zantac use might be linked to breast cancer. Our ranitidine cancer lawyers are presently investigating the link between numerous types of cancer and the use of Zantac. We strongly believe there is a causal link between Zantac and liver cancer. The CDC has expressly stated that NDMA can prove harmful to the livers of both humans and animals
Symptoms of liver cancer include: loss of appetite, upper abdominal pain, jaundice, vomiting and/or nausea and white chalky stools. We are presently representing many individuals who have been diagnosed with primary liver cancer as a result of Zantac use. The liver along with our heart is the most important organ. In fact, the liver serves to detoxify chemicals and filter blood passing through the body. Cancer cells often begin in other areas and then spreads to the liver.
A Brief History of Zantac
Zantac, known as ranitidine in its generic form, is a well established and widely used over-the-counter and prescription medication to fight heartburn. First introduced in 1981, it was the world’s biggest-selling prescription drug in 1988 before it became available for over-the-counter use. Even though several more effective medications have eclipsed Zantac, it is still widely used and less expensive than the others. It was the 50th most prescribed medication in the United States, with more than 15 million prescriptions in 2016.
The manufacture and distribution of this popular acid reducer came to a halt in September 2019 as the toxin N-nitrosodimethylamine (NDMA) was found in the drug from several different manufacturers. This nitrosamine impurity is a possible human carcinogen, even at low levels.
Currently, there is not enough scientific evidence for the United States Food and Drug Administration (FDA) to determine how long NDMA has been present in ranitidine. If you currently take this medication or used it in the past, and you think you are experiencing Zantac cancer symptoms, contact your physician or another health care professional to discuss your treatment options and a dangerous drugs lawyer at our firm to determine your course of action.
What is NDMA?
NDMA can also be formed during the cooking of foods, especially food such as cured meats and fish because they contain sodium nitrite as a preservative. It is also found in:
- Alcoholic beverages
- Rubber products
- Tobacco smoke
Preliminary testing by the FDA shows some samples of Zantac and ranitidine contain higher levels of NDMA than food.
Although human studies are limited, NDMA is listed as a probable carcinogen to both animals and humans. It is still unknown how ranitidine was contaminated with NDMA, as found in laboratory tests.
There is a possibility that ranitidine is unstable and breaks down on its own to form NDMA. The FDA-approved acceptable amount of NDMA intake is 96 nanograms (ng) per day. Studies have shown that when ranitidine mixes with the gastric fluid and sodium nitrites that stimulate the digestion process, high amounts of NDMA are produced. Exposure to simulated stomach conditions caused ranitidine to produce approximately 304,500 ng of NDMA per tablet.
It is also possible that generic versions of Zantac are contaminated with NDMA when manufactured in other countries without strict quality control standards.
The Food and Drug Administration reports that its independent testing has shown that the heartburn medications Pepcid, Tagamet, Nexium, Prevacid, and Prilosec do not contain the chemical NDMA.
NDMA Previously Found in Other Medications
Angiotensin II Receptor blockers, including Valsartan, Losartan, and Irbesartan, were also recalled for NDMA contamination in 2018. In studies with these drugs, there did not seem to be a link to an increased short-term risk of getting cancer, but there was an increased risk of some single cancer outcomes observed. Further studies are warranted, and, until more information is available, many patients are steering clear of Zantac and opting for alternative medications such as Prevacid or Prilosec, which the FDA says are not contaminated with NDMA.
Common Zantac Cancer Symptoms
If you or someone you love takes Zantac or did in the past, it is crucial to be aware of cancer symptoms. Knowing these symptoms can potentially save your life. Common Zantac cancer symptoms include:
- Unintentional weight loss
- Poor appetite
- Nausea or vomiting
- Bloody or tarry stools (an indicator of intestinal bleeding)
- Light-colored or greasy stools
- A change in bowel habits
- Symptoms of anemia such as fatigue, dizziness, and weakness
- New abdominal pain unrelated to heartburn
- Back pain
- Yellowing of the skin or eyes
- Dark urine
- Blood in the urine
- Urinary urgency or incontinence
- Painful urination
- Itchy skin
If you are experiencing any of these Zantac cancer symptoms, see your doctor as soon as possible. Additionally, you will want to consult a product liability attorney if you have a history of prescription or over-the-counter use of Zantac or ranitidine.
What are Your Chances of Getting Cancer from Zantac?
NDMA exposure is suspected to increase the risk of several different cancers, including tongue, esophagus, lung, pancreas, liver, kidney, and bladder cancers. You should discuss your concerns about getting cancer from the use of Zantac with your doctor. There is no formula to determine what your risk might be. However, through animal testing, it is known that the higher doses and the longer exposures to NDMA increase the risk of test animals getting cancer. The incidence of liver tumors increased, and survival rates decreased in a dose-dependent manner when studied in lab rodents.
Zantac Cancer Risk
The FDA has requested that companies recall their ranitidine if testing shows levels of NDMA higher than the acceptable daily intake of 96 ng or 0.32 parts per million for ranitidine. Although the FDA advisory states that the level of NDMA contamination is minimal in Zantac, some levels were 3,000 to 26,000 times more than what the FDA says is safe.
Zantac Recalls in the United States
Drug manufacturers may issue a voluntary recall to remove products that violate FDA regulations. Recalls protect public health from products that could present a risk of harm or gross deception by the drug manufacturer. Distributors and manufacturers can issue a voluntary recall at any time, although sometimes the FDA requests a recall. Either way, the FDA monitors the recall.
Multiple voluntary recalls have been issued for Zantac and ranitidine drugs. In mid-September 2019, the FDA announced to the public that NDMA was found in ranitidine samples. On September 24, 2019, the first voluntary recall was issued concerning this finding, and Sandoz ranitidine capsules were recalled. Two days later, a voluntary recall was issued for over-the-counter ranitidine tablets (both 75 mg and 150 mg), labeled and sold by Walgreens, Walmart, and Rite-Aid and manufactured by Apotex Corp.
In late October 2019, pharmaceutical company Sanofi announced a voluntary recall of their over-the-counter ranitidine products Zantac 150, Zantac 150 Cool Mint, and Zantac 75. Over the next few days, voluntary recalls were also issued for ranitidine oral solution from Lannett Company, Inc. and Novitium Pharma’s 150mg and 300mg capsules. Between November 2019 and January 2020, an additional eight recalls of ranitidine products were issued.
When Do You Need To Hire A Zantac Cancer Lawyer?
If you believe your cancer was caused by Zantac or ranitidine you may need the help of a Zantac Cancer Lawyer. In order to pursue your case, your Zantac lawyer will help you to prove 3 things:
- that you used Zantac or ranitidine,
- that you have cancer,
- and that the two are connected.
Proving that you used Zantac or ranitidine. Those who are interested in pursuing a cancer lawsuit caused by Zantac will of course have to first prove that they actually took the medication Zantac or ranitidine. The easiest way to prove this would be to contact your doctor or pharmacy to get records of your prescriptions. If you bought the medication over-the-counter, it may be a little hard to prove that you took the medication but, through the help of your lawyer, it can be done using receipts and statements from your doctor.
Proving that you have cancer. Zantac and ranitidine are most commonly known to be harmful in the sense that they could cause cancer. So in order to file a lawsuit, you will not only have to prove that you have cancer but that the type of cancer you have is linked to NDMA. These two stipulations can easily be achieved with the help of your lawyer, doctors, and medical experts.
Proving that the two are connected. Proving that your consumption of Zantac or ranitidine are linked is where all lawsuits get tricky. Generally, there is information, studies, and experts that can all testify to the fact that the two are linked. But you must also show that you consumed enough of the medication for it to have been dangerous. There are two things that can help prove that your consumption of Zantac caused your cancer: how much of the medication you took and how long you took it. The longer you took the medication, and the more of it you took, the more likely it is that your cancer and your consumption of the drug are connected. This connection will be further developed with the help of your legal and medical expert team. This is why it is so important to have an experienced Zantac Cancer Lawyer on your side.
Read What Leading Attorneys Say About Hiring a Zantac Cancer Attorney
We asked some of the top attorneys from around the country to answer a simple yet important question: “What are my legal rights if I’ve been diagnosed with cancer as a result of using Zantac?”
Here are their responses:
Steve A Barnes, Esq
On April 1, 2020 the FDA directed drug manufacturers to immediately withdraw from the market all Zantac and generic ranitidine drugs.
This followed a petition filed with the FDA by the online pharmacy company, Valisure, alerting the government to it’s findings of “extremely high levels of NDMA (a known carcinogen)… in every lot tested”.
NDMA is known to occur in many foods and beverages and is carcinogenic in very low doses. For this reason, the FDA has set acceptable daily intake of NDMA at 96 nanograms (96 billionths of a gram). Through its internal scientific studies, the online pharmacy, Valisure, reported that a single 150 mg Zantac (ranitidine) tablet produced 304,500 ng of NDMA, over 3,000 times the FDA recommended daily limit.
Why is this occurring? In its petition, Valisure concludes that the problem is not contamination of the drug. Instead, NDMA is likely formed in the body due to the inherent instability of the ranitidine molecule. This means that because of the way Zantac (ranitidine) is metabolized in the human body NDMA is formed in unacceptable levels. A 2016 study at Stanford University found that patients taking 150 mg of Zantac had NDMA levels in their bodies exceeding 47,000 ng, nearly 500 times the FDA recommended daily limit. Since most of the NDMA would have been eliminated before reaching the urine, the level in the human body may have been much higher.
In 2011 a study was published in the American Journal of Clinical Nutrition which concluded that “dietary NDMA intake was significantly associated with increased risk of cancer in men and women and that “NDMA was associated with increased risk of gastrointestinal cancers.”
This was part of the European Prospective Investigation into Cancer and Nutrition (EPIC), one of the largest cohort studies in the world.
These are just a few of the scientific studies that should have been known to the manufacturer of ranitidine products like Zantac. There are others. If you have been diagnosed with cancers such as bladder, breast, kidney, prostate, thyroid, testicular, uterine, esophageal/throat, intestinal, liver, nasal, ovarian, pancreatic, or stomach you should reach out to a law firm with experience in handling these cases. Presently, all lawsuits have been consolidated into what is known as an MDL (Multi District Litigation) in the Southern Federal District of Florida. Therefore, you should give serious consideration to retaining a Florida based law firm.
Whitney Butcher, Esq.
If you have been diagnosed with bladder, kidney, stomach, or another cancer after taking Zantac, you may be able to receive compensation for your medical expenses, time spent out of work, and physical pain and emotional suffering as a result of this cancer diagnosis.
The FDA recalled Zantac earlier this year due to the link between this medication and cancer, so if you have been diagnosed after taking the medication it is important to speak to attorney to protect any legal rights you may have.
Ryan McKeen, Esq.
Many medical device and drug manufacturers have a duty to create products that are reasonably safe for consumers. Before a medicine is made available, companies may be required to extensively test a product and list all potential negative side effects related to the drug’s intended use. Among the companies that must perform these tests is Sanofi, which produces the common heartburn medication Zantac.
On April 1, 2020, the United States Food and Drug Administration (FDA) issued a recall of Zantac and similar ranitidine products after N-Nitrosodimethylamine (NDMA) was found in the drug when handled under certain conditions. NDMA is classified by the FDA and other organizations as a probable human carcinogen.
Whenever a pharmaceutical company creates a product that results in negative effects from intended use, and they do not disclose these effects to the public, individuals harmed by that drug may have the ability to pursue compensation. Because of this, an individual who took Zantac or ranitidine, and later developed cancer, might be able to file a lawsuit.
Sol Weiss, Esq
You must have taken Zantac for more than a year and been diagnosed with any one of the following types of cancer ; Bladder , Esophageal, Kidney, Colon or rectal, Intestinal, Liver, Pancreatic, Prostate(less than 60 years old, Stomach, Testicular , Brain or Breast. The science behind why Zantac causes cancer is rapidly developing.
Cases filed in Federal Court have been consolidated for all pretrial purposes before the honorable Judge Robin L Rosenberg in the Southern District of Florida. At Anapol Weiss we are investigating cases for more than 1500 clients.
Our team consisting of four lawyers and four paralegals will review your medical records and proof of drug use to protect your legal rights against Sanofi and other makers of Zantac.
John Gomez, Esq.
Millions of heartburn sufferers relied on the over the counter and prescription versions of Zantac – or its generic equivalents sold as “Ranitidine” under brands from retailers like Walmart and CVS – to deal with the burning pain of heartburn. However, research has recently linked the brand name and generic drugs containing ranitidine to a variety of cancers. As a result, the U.S. government has ordered all drugs containing ranitidine pulled from the shelves. In the meantime, former users of the drug diagnosed with cancer are left facing a formidable diagnosis and questions about their legal rights and what to do next.
If you are facing a cancer diagnosis after prolonged Zantac or ranitidine use, you may have a legal right to compensation for your damages. If you retain a lawyer to represent you for your potential claim, your counsel could pursue damages for past and future medical expenses resulting from your injuries/diagnoses, past and future pain and suffering (physical and mental) caused by your injuries as well as the treatment and recovery process, past and future lost wages, past and future loss of earning capacity, past and future loss of enjoyment of life, and/or punitive damages, if appropriate and depending on applicable laws.
In April of 2020, the FDA announced that all Zantac brand heartburn drugs, prescription and over-the counter, should be immediately pulled from the market because of potential NDMA (N-nitrosodimethylamine) contamination, a chemical linked to cancer. The manufacturers of Zantac and ranitidine had a responsibility to ensure that their products were reasonably safe and effective for consumer use. However, by manufacturing products containing a carcinogen at levels exceeding what is considered safe, these drug makers failed to meet that responsibility.
Consumer lawsuits filed throughout the country and coordinated in the Southern District of Florida’s Multidistrict Litigation (“MDL”) allege that Zantac and ranitidine drugmakers manufactured, marketed and sold a product they knew or should have known had been contaminated with an industrial chemical known to cause cancer. Despite their knowledge of this potential risk, the manufacturers of Zantac and ranitidine made the choice not to disclose this risk to the FDA or consumers. If you have been diagnosed with cancer after prolonged Zantac or ranitidine use, you have the right to hold the manufacturing drug company accountable and to monetary recovery for your injuries.
Jay Kelley, Esq.
The FDA reported the over the counter and prescription medication Zantac ( ranitidine) contains N-nitrosodimethylamine a cancer causing chemical when exposed to heat for even limited time, such as in a delivery truck.
Symptoms of exposure may include: fever, nausea, vomiting, jaundice, dizziness and/or cramping.
If an individual used Zantac for 5 years and has received a cancer diagnosis they may have a legal remedy available. The cases are proceeding in a Multi-district litigation ( MDL) currently. Clients with recent cancer diagnosis and a Zantac use history should contact an attorney to see if their diagnosis is entitled to compensation.
Stanley Gipe, Esq
If you have been diagnosed with cancer as a result of using Zantac you are not alone. The issue first came to light when the online pharmacy Valisure found unacceptably high levels of the probable cancer-causing substance N-nitrosodimethylamine (NDMA) in ranitidine products. Valisure is unique by testing every batch of drugs it sells for impurities. in 2019, Adam Clark-Joseph, cofounder of Valisure, ordered ranitidine syrup, prescribed to treat reflux in his young daughter. When the ranitidine tested positive for NDMA, Valisure began testing other drugs from other manufacturers.
“Every batch of every bottle of every manufacturer showed the same results, tremendously high formation of NDMA,” says CEO David Light. Ranitidine is sold in the United States under the brand name Zantac. The FDA took notice of these findings and issued a recall for Zantac in 2020. Prior to the recall recalled by the FDA, an estimated 15,000,000 Americans were taking prescription levels of Zantac and millions more were taking the over the counter version of the drug. With heartburn affecting an estimated 60,000,000 Americans annually, and millions more worldwide, Zantac became the best-selling drug in the world.
The recent scientific studies and FDA recall have caused many people to begin to question whether or not Zantac caused their the cause of their cancer and lawsuits are being fought to get fair compensation for those diagnosed with cancer as a result of using Zantac. If you have been diagnosed with cancer and have used Zantac in the past it is important to know you are not alone in this fight. Thousands of people just like you are pursuing their claims right now. The time frame for bringing a Zantac related cancer claim is limited and much of the work is already being done by firms currently litigating this issue. If you or a loved one were diagnosed with cancer after using Zantac your time to make a claim is limited. It is important that you team with a qualified Zantac cancer lawyer to represent you in this fight as soon as possible. ”
Larry Nussbaum, Esq
Time and time again, large pharmaceutical companies are only worried about selling their products and turning large profits. As a result, we all suffer from the potential negative effects of these drugs such as Zantac. These companies know the dangers these drugs present. However, they continuously make the conscious decision to ignore the facts and hide the truth from the general public for their own selfish monetary gains. If you or a loved one has been diagnosed with cancer as a result of using Zantac, it was not accidental, but rather you are a victim. Us lawyers are here to help. You have a right to file a lawsuit and may be eligible for a large settlement.
Prior to taking Zantac you should have been informed of all the risk and dangers associated with it; and a chance to make your own educated decision if the risks were worth it. Cancer is no joke and together we should all make the big manufacturers pay for their deceitful tactics. If you knew you could get cancer from taking Zantac, would you still have taken it? Regardless of how you may have answered the prior question, if you took Zantac and were diagnosed with cancer the time is now to contact a lawyer and make the pharmaceutical companies pay. We may not be able to rid you of the cancer, but together we can stop this from happening to others in the future and get you financially compensated all at the same time.
Contact an Experienced Florida Zantac Attorney
When you are suffering from an ailment, like heartburn or a headache, you have right to assume the OTC medication in your cabinet is safe. Additionally, if you seek treatment from a medical professional and they prescribe you a medications, you have a right to assume that what you are taking is safe and will work as intended. Unfortunately, this is not always the case, and each year, people are injured by defectively manufactured prescription drugs, unknown chemicals, and negligent companies. In some cases, the injury is caused by a medical professional’s negligence in prescribing a particular drug.
Drugs like Zantac have the potential to cause severe injuries to those that use it. The people that suffer these injuries deserve compensation for the damages that they suffered due to the negligence of liable parties that did not take the proper precautions when making such a drug available to consumers. Dolman Law Group specializes in holding these groups accountable for their negligence and recovering settlements for those that have suffered because of this negligence. Contact us today to get the compensation you deserve from a Zantac Lawsuit. We are handling Zantac lawsuits nationwide and have formed relationships with fellow leading attorneys and law firms nationwide in order to assist victims in all fifty states. As a Zantac law firm, we will bring in local counsel when necessary to comport with the rules in each jurisdiction.
If you have been prescribed a medication that you believe may have caused an injury, please contact the attorneys at Sibley Dolman/Dolman Law Group for a free consultation today. You can reach our office by either calling (833) 606-DRUG  or contacting us online. The ideal attorney for Zantac lawsuit has the resources necessary to thoroughly investigate your claim and take on the biggest of corporate giants like Sanofi.
Dolman Law Group
800 North Belcher Road
Clearwater, FL 3375
(833) 606-DRUG